John Wesley Long II (1824-1863) of Randolph County, NC, was the son of Sabra Ramsey (b. 1784) and Dr. John Wesley Long, Jr. (1785-1857). John Wesley entered the University in 1840, joined the Dialectic Society, and graduated in 1844. He received his MD in 1848 from Jefferson Medical College in Philadelphia and became a physician. In 1852 he married Nancy Margaret Troy (1835-1904); their son, John Wesley Long III (1859-1926), survived to adulthood.